Secret Squirrel
Rules: Played as normal, but each player's low down card, and all others of that rank in his hand, count as wild cards for him. (So if your low down card is a 7, all 7s in your hand are wild.) Common Variation: if the dealer declares it in advance, you may pay 50 cents in order to receive your last card face-up.
Analysis: With everyone guaranteed at least one wild card, and two being common, this usually falls to at least a boat. Four of a kind is common, and five of a kind not terribly rare.
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Variants
That is: deal six cards face-down to each player. Don't look at your cards. Flip the top card of the deck, and play Mexican Sweat as usual. However, in the final showdown, your lowest rank is wild for you only, similar to Secret Squirrel.